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Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...

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Related Experiment Video

Updated: May 18, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

Childhood tuberculosis and malnutrition.

Devan Jaganath1, Ezekiel Mupere

  • 1David Geffen School of Medicine at the University of California, Los Angeles, USA.

The Journal of Infectious Diseases
|October 4, 2012
PubMed
Summary

Malnutrition predicts childhood tuberculosis and worsens outcomes, but nutritional supplementation shows no clear benefits. More research is needed on how nutrition impacts pediatric tuberculosis risk and progression.

Area of Science:

  • Pediatric infectious diseases
  • Nutritional science
  • Immunology

Background:

  • Childhood tuberculosis (TB) and malnutrition are significant global health issues.
  • Malnutrition is linked to increased TB risk and poorer disease outcomes in children.
  • Existing research highlights potential mechanisms, including immune development and vitamin D receptor genotypes.

Purpose of the Study:

  • To review the current understanding of the relationship between malnutrition and tuberculosis in children.
  • To identify research gaps concerning nutritional status, TB risk, progression, and treatment outcomes in pediatric populations.
  • To emphasize the need for further investigation into nutritional interventions for childhood TB.

Main Methods:

  • Literature review of studies examining malnutrition and tuberculosis in pediatric populations.

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An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis
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An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis

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Last Updated: May 18, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis
09:34

An Automated Culture System for Use in Preclinical Testing of Host-Directed Therapies for Tuberculosis

Published on: August 16, 2021

  • Analysis of evidence linking nutritional status to TB incidence, severity, and outcomes.
  • Synthesis of findings on the role of nutritional supplementation in managing childhood TB.

    • Main Results:

    • Malnutrition is a recognized predictor of tuberculosis disease in children.
    • Evidence suggests malnutrition is associated with worse tuberculosis outcomes.
    • Nutritional supplementation has not yet demonstrated significant benefits for children with tuberculosis.

    Conclusions:

    • There is a critical need for research on the interplay between nutritional status and tuberculosis in children.
    • Further studies should explore how nutritional status influences the risk and progression of pediatric TB.
    • Investigating the efficacy of nutritional supplementation in improving clinical outcomes or preventing childhood TB is essential.