Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ethical Issues01:27

Ethical Issues

Nurses are essential in patient care, upholding the ethical principles of their profession and effectively navigating ethical dilemmas. Neglecting ethical issues can lead to inadequate patient care, compromised therapeutic relationships, and moral distress among healthcare workers.
Ethical Concerns in Healthcare:
Stages of General Anesthesia01:22

Stages of General Anesthesia

Various sedation levels offer significant advantages in facilitating procedural interventions for patients undergoing medical or invasive surgical procedures. These levels span from anxiolysis to general anesthesia, providing a spectrum of sedative effects to cater to specific patient needs. Anxiolysis reduces anxiety and is achieved through minimal sedation, enabling patients to remain awake and responsive while feeling more at ease during the procedure. This level can benefit minor...
Ethical Dilemmas II01:30

Ethical Dilemmas II

Resolving an ethical dilemma in healthcare involves a systematic approach that considers every aspect of the issue, respecting both the patient's needs and values and the healthcare professional's ethical obligations. Here are potential steps to resolve an ethical dilemma:
Parenteral Anesthetics: Overview01:24

Parenteral Anesthetics: Overview

Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
Inhalational Anesthetics: Overview01:20

Inhalational Anesthetics: Overview

Inhalation anesthetics are drugs that induce general anesthesia upon inhalation. They work by increasing the sensitivity of GABAA receptors or inhibiting NMDA receptors, leading to a decrease in central nervous system activity. The depth of anesthesia can be rapidly adjusted by changing the concentration of the inhaled gas. Some common examples of inhalational anesthetics include volatile liquids like isoflurane, desflurane, sevoflurane and gases like xenon and nitrous oxide. Isoflurane, a...
Sedatives and Hypnotics: Overview01:23

Sedatives and Hypnotics: Overview

Sedatives are drugs that alleviate anxiety, while hypnotics induce sleep. Both classes of medication suppress neuronal activity, leading to a calming effect for sedatives and facilitating sleep for hypnotics.
Sedative-hypnotics are categorized into barbiturates, benzodiazepines (BZDs), and non-benzodiazepines or Z-drugs. These drugs work by suppressing central nervous system activity, and this suppression is dose-dependent. Older sedative medications, like barbiturates, follow a linear curve in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Artificial hydration at the end of life: balancing benefits and risks in the absence of conclusive evidence.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2020
Same author

Limitations associated with managing chronic low back pain.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2016
Same author

Selective detection of bacteria in urine with a long-range surface plasmon waveguide biosensor.

Biomedical optics express·2015
Same author

I did not intend to demean hospice at home professionals.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2013
Same author

Implications for carers of terminally ill patients dying at home.

Nursing standard (Royal College of Nursing (Great Britain) : 1987)·2013
Same author

Home births.

RCM midwives journal : official journal of the Royal College of Midwives·2002

Related Experiment Video

Updated: May 18, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Ethical issues around continuous deep sedation without hydration.

Paul Beland1

  • 1St Barnabas Lincolnshire Hospice.

Nursing Times
|October 5, 2012
PubMed
Summary
This summary is machine-generated.

Continuous deep sedation without hydration in palliative care may be a moral and clinical equivalent to slow euthanasia. This review examines survival, fluid retention, and thirst, questioning the practice of withholding fluids in end-of-life care.

More Related Videos

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers
14:52

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers

Published on: January 13, 2018

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
09:36

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device

Published on: September 24, 2020

Related Experiment Videos

Last Updated: May 18, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers
14:52

Recording Brain Electromagnetic Activity During the Administration of the Gaseous Anesthetic Agents Xenon and Nitrous Oxide in Healthy Volunteers

Published on: January 13, 2018

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
09:36

Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device

Published on: September 24, 2020

Area of Science:

  • Palliative Care Medicine
  • Bioethics
  • Oncology

Background:

  • Continuous deep sedation is used in palliative care for refractory symptoms.
  • Withholding parenteral fluids is a practice at the end of life for sedated patients.
  • Ethical and clinical implications of this practice require examination.

Purpose of the Study:

  • To evaluate if continuous deep sedation without hydration is a moral and clinical equivalent to slow euthanasia.
  • To review evidence on survival, fluid retention, and thirst in this context.

Main Methods:

  • Literature review of existing studies and ethical analyses.
  • Focus on evidence related to length of survival.
  • Examination of data on fluid retention and thirst.

Main Results:

  • Evidence supporting or questioning the practice of withholding fluids is limited.
  • The practice's impact on survival, fluid retention, and thirst is not definitively established.
  • Ethical parallels to slow euthanasia are debated.

Conclusions:

  • The practice of withholding parenteral fluids in sedated, end-of-life cancer patients warrants further ethical and clinical scrutiny.
  • More research is needed to clarify the moral and clinical equivalence to slow euthanasia.
  • Palliative care guidelines should address this practice explicitly.