Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Pulse rhythm

Pulse rhythm

Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...

Electrophysiology of Normal Cardiac Rhythm

Electrophysiology of Normal Cardiac Rhythm

The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase of...

Pulse

Pulse

When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
The pulse serves as a clinical indicator...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Integrating molecular and physiological approaches to quantify genetic controls for wheat development and improve phenotyping.

Journal of experimental botany·2026

Same author

Tele-Electrocardiography and Mortality: Clinical Outcomes in Digital Electrocardiography Cohort-Data from Belo Horizonte, Brazil (CODE-BH).

Global heart·2026

Same author

CODE-II: a large-scale dataset for artificial intelligence in ECG analysis.

NPJ digital medicine·2026

Same author

A Cell-Based Reporter Gene Assay for TNF-α Neutralization: Analytical Qualification and Application to Adalimumab and Its Biosimilars.

Pharmaceutical research·2026

Same author

The Effects of Conservative Fluid Management and Active Deresuscitation on Markers of Tissue Perfusion, Kidney Injury, and Vascular Injury in Critically Ill Adults: A Secondary Analysis of the Role of Active Deresuscitation After Resuscitation-2 (RADAR-2) Trial.

Critical care explorations·2026

Same author

Clinicopathological and Prognostic Characteristics of Gastric-Type Endocervical Adenocarcinoma: A Nested Case-Control Study.

Cancers·2026

Search research articles

Related Experiment Video

Updated: May 18, 2026

Translational Rabbit Model of Chronic Cardiac Pacing

Translational Rabbit Model of Chronic Cardiac Pacing

Published on: January 6, 2023

Implanted cardiac pacemaker pulses as recorded from the body surface.

Shen Luo¹, Paul Johnston, Peter W Macfarlane

¹Cardiac Science Corporation, Deerfield, WI, USA. shenl@uwalumni.com

Journal of Electrocardiology

|October 5, 2012

Summary

Contemporary pacemaker pulse characteristics reveal that over 50% fall below AAMI/IEC detection thresholds. Current pacemaker pulse detection standards require updates to accurately reflect these findings from body surface ECGs.

More Related Videos

Bidirectional Electrical and Optoelectronic Interfaces in Healthy and Ischemic Ex Vivo Rat Hearts

Bidirectional Electrical and Optoelectronic Interfaces in Healthy and Ischemic Ex Vivo Rat Hearts

Published on: July 18, 2025

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Published on: April 11, 2025

Related Experiment Videos

Last Updated: May 18, 2026

Translational Rabbit Model of Chronic Cardiac Pacing

Translational Rabbit Model of Chronic Cardiac Pacing

Published on: January 6, 2023

Bidirectional Electrical and Optoelectronic Interfaces in Healthy and Ischemic Ex Vivo Rat Hearts

Bidirectional Electrical and Optoelectronic Interfaces in Healthy and Ischemic Ex Vivo Rat Hearts

Published on: July 18, 2025

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Published on: April 11, 2025

Area of Science:

Cardiovascular Electrophysiology
Biomedical Engineering
Medical Device Technology

Background:

Pacemaker pulses are crucial signals on electrocardiograms (ECGs) for monitoring device function.
Existing standards for detecting pacemaker pulses (AAMI/IEC) may not reflect the characteristics of modern devices.
Accurate detection of pacemaker pulses is essential for patient safety and device management.

Purpose of the Study:

To analyze the characteristics of contemporary pacemaker pulses recorded from the body surface.
To evaluate the suitability of current AAMI/IEC thresholds for pacemaker pulse detection.
To propose improvements for pacemaker pulse annotation and detection standards.

Main Methods:

Collected 12-lead ECGs from 140 patients (68 ± 12 years, 71% males) at a high sampling rate (32,000 samples/sec).
Manually annotated pacemaker pulses using the high-sampling rate data stream.
Analyzed pulse durations and amplitudes against established AAMI/IEC thresholds.

Main Results:

Pacemaker pulse durations were found to be stable.
Significant variations were observed in pacemaker pulse amplitudes.
Over 50% of analyzed pulses had durations <0.5 ms or amplitudes <2 mV, falling below AAMI/IEC detection thresholds.

Conclusions:

Current AAMI/IEC standards for pacemaker pulse detection are inadequate for contemporary devices.
Updated standards are necessary to ensure accurate pacemaker pulse detection on ECG reports.
A high-sampling rate database is recommended as a standard for testing pacemaker annotation and detection.