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Related Concept Videos

Current Density01:21

Current Density

The total amount of current flowing through one unit value of a cross-sectional area is referred to as current density. If the current flow is uniform, the amount of current flowing through a conductor is the same at all points along the conductor, even if the conductor area varies. The current density consists of the local magnitude and direction of the charge flow, which varies from point to point. Current density is measured in amperes per meter square, and direction is defined as the net...

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Related Experiment Video

Updated: May 18, 2026

Porous Substrate-Based Electroporation with Transepithelial Electrical Impedance Monitoring
08:06

Porous Substrate-Based Electroporation with Transepithelial Electrical Impedance Monitoring

Published on: September 27, 2024

Current density imaging during tissue electroporation.

F Bajd1, M Kranjc, D Miklavčič

  • 1Jozef Stefan Institute, Ljubljana, Slovenia.

Prilozi
|October 6, 2012
PubMed
Summary

External electric pulses enhance tissue permeability during electroporation. Monitoring current density imaging and magnetic resonance electric impedance tomography optimizes these electric field parameters for better treatment.

Area of Science:

  • Biomedical Engineering
  • Medical Physics

Background:

  • Electroporation uses electric pulses to increase cell membrane permeability for treatments.
  • Optimizing electric field distribution is crucial for effective electroporation.
  • Current density and electric field monitoring are key to parameter optimization.

Purpose of the Study:

  • To investigate methods for monitoring electric field distributions during electroporation.
  • To highlight the role of current density imaging (CDI) and magnetic resonance electric impedance tomography (MREIT) in optimizing electroporation.

Main Methods:

  • Applying external electric pulses to target tissue.
  • Utilizing current density imaging (CDI) for real-time monitoring.
  • Employing magnetic resonance electric impedance tomography (MREIT) for electric field mapping.

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High-Throughput Capable Three-Dimensional Tissue Model for Quantification of Electroporation Thresholds
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High-Throughput Capable Three-Dimensional Tissue Model for Quantification of Electroporation Thresholds

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The Fabrication and Operation of a Continuous Flow, Micro-Electroporation System with Permeabilization Detection
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The Fabrication and Operation of a Continuous Flow, Micro-Electroporation System with Permeabilization Detection

Published on: January 7, 2022

Related Experiment Videos

Last Updated: May 18, 2026

Porous Substrate-Based Electroporation with Transepithelial Electrical Impedance Monitoring
08:06

Porous Substrate-Based Electroporation with Transepithelial Electrical Impedance Monitoring

Published on: September 27, 2024

High-Throughput Capable Three-Dimensional Tissue Model for Quantification of Electroporation Thresholds
08:23

High-Throughput Capable Three-Dimensional Tissue Model for Quantification of Electroporation Thresholds

Published on: August 19, 2025

The Fabrication and Operation of a Continuous Flow, Micro-Electroporation System with Permeabilization Detection
10:34

The Fabrication and Operation of a Continuous Flow, Micro-Electroporation System with Permeabilization Detection

Published on: January 7, 2022

Main Results:

  • Externally applied electric pulses increase membrane permeability.
  • Electric currents and their distributions within the tissue can be monitored.
  • CDI and MREIT enable visualization of electric field parameters.

Conclusions:

  • CDI and MREIT are effective tools for monitoring electroporation.
  • Monitoring electric fields aids in optimizing electroporation parameters for enhanced efficacy.
  • Improved understanding of electric field dynamics can advance electroporation therapies.