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Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury
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Diffusion tensor imaging atlas-based analyses in major depression after mild traumatic brain injury

Vani Rao1, Michelle Mielke, Xin Xu

  • 1Department of Psychiatry, Johns Hopkins School of Medicine, Baltimore, MD, USA. vrao@jhmi.edu

The Journal of Neuropsychiatry and Clinical Neurosciences
|October 6, 2012
PubMed
Summary

Early brain imaging after mild traumatic brain injury (mTBI) may predict depression. White-matter abnormalities in fronto-temporal regions were linked to developing depression post-mTBI in a pilot study.

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DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...