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Published on: February 11, 2018
A facile fabrication of spherical and beanpod-like magnetic-fluorescent particles with targeting functionalities
Yan-Lin Liu1, Ji-Lin Zhang, Gong Cheng
1State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, People's Republic of China.
Abstract:
Magnetic-fluorescent particles with targeting functionalities were fabricated by a modified Stöber method and two shapes (spherical and beanpod-like) were obtained by simply tuning the reaction temperature. The two multifunctional probes combined the useful functions of magnetism, fluorescence and FA (folic acid)-targeting recognition into one entity. The products were characterized by scanning electron microscopy, transmission electron microscopy, photoluminescence spectroscopy, confocal laser scanning microscopy, by a superconducting quantum interference device and by Fourier transform infrared spectroscopy. The experimental results show that the products possessed rapid magnetic response, relatively strong fluorescent signal, higher photostability and FA-targeting recognition as well as good water-dispersibility, suggesting that they would have potential medical applications in biolabeling and bioimaging.
