Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Qualitative characterization of the composition of dental thermoplastic polymers by pyrolysis GC-MS.

Dental materials : official publication of the Academy of Dental Materials·2026
Same author

Ex-vivo study investigating modified pulp-capping glass-ionomers.

Dental materials journal·2026
Same author

Stored L-PRF membranes: safety, morphology, tensile properties, and cell viability-an in vitro pilot study.

Scientific reports·2026
Same author

Highly alkaline mineral trioxide aggregate (MTA) affects restorative materials.

Dental materials : official publication of the Academy of Dental Materials·2026
Same author

Novel chemical initiator using borate salt and sulfonic acid group-containing copolymer for an MMA-based adhesive resin cement.

Dental materials : official publication of the Academy of Dental Materials·2026
Same author

3D digital data analysis to identify factors influencing debonding of CAD-CAM resin composite molar crowns: A 4-year clinical study.

Journal of prosthodontic research·2026

Related Experiment Video

Updated: May 18, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration
10:28

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Bone tissue response to implant surfaces functionalized with phosphate-containing polymers.

Marcio Vivan Cardoso1, Amol Chaudhari, Yasuhiro Yoshida

  • 1Leuven BIOMAT Research Cluster, School of Dentistry, Oral Pathology and Maxillofacial Surgery, Catholic University of Leuven, Leuven, Belgium.

Clinical Oral Implants Research
|October 9, 2012
PubMed
Summary

Polyphosphoric acid (PPA) and phosphorylated pullulan (PPL) treatments enhanced bone regeneration around implants in rabbits. PPA improved bone-to-implant contact, while PPL increased bone fraction near the implant surface after four weeks.

Keywords:
implant roughnessosseointegrationsurface characterizationsurface functionalizationtitanium

More Related Videos

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro
14:49

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

Published on: April 15, 2022

An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
11:51

An Improved Mechanical Testing Method to Assess Bone-implant Anchorage

Published on: February 10, 2014

Related Experiment Videos

Last Updated: May 18, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration
10:28

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro
14:49

Direct and Indirect Culture Methods for Studying Biodegradable Implant Materials In Vitro

Published on: April 15, 2022

An Improved Mechanical Testing Method to Assess Bone-implant Anchorage
11:51

An Improved Mechanical Testing Method to Assess Bone-implant Anchorage

Published on: February 10, 2014

Area of Science:

  • Biomaterials Science
  • Orthopedic Research
  • Tissue Engineering

Background:

  • Inorganic polyphosphates are known to stimulate osteoblast-like cells in vitro.
  • Understanding in vivo bone regeneration is crucial for dental and orthopedic implant success.

Purpose of the Study:

  • To evaluate the in vivo bone regeneration efficacy of implants treated with polyphosphoric acid (PPA) and phosphorylated pullulan (PPL).

Main Methods:

  • Two implant surface roughness types (R1, R2) were treated with distilled water, 10% PPA, or 10% PPL.
  • Implants were placed in rabbit tibias, with histological and histomorphometrical analysis performed at 1 and 4 weeks.
  • Bone-to-implant contact (BIC) and bone fraction (BF) were measured at 100 and 500 μm from the implant surface.

Main Results:

  • After 4 weeks, PPA treatment significantly increased BIC compared to the control group.
  • PPL treatment significantly increased BF within 100 μm of the implant surface compared to the control.
  • No significant differences in BF were observed at 500 μm, and surface roughness did not impact BIC or BF.

Conclusions:

  • Implant surface treatment with phosphate-containing polymers, such as PPA and PPL, shows potential to enhance osseointegration.
  • These findings suggest a promising role for phosphate-based surface modifications in improving implant performance.