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Platelet-activating factor, histamine, and tryptase levels in human anaphylaxis

Peter Vadas1, Boris Perelman, Gary Liss

  • 1Division of Allergy and Clinical Immunology, Department of Medicine, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada. vadasp@smh.ca

The Journal of Allergy and Clinical Immunology
|October 9, 2012
PubMed
Summary

Platelet-activating factor (PAF) levels strongly correlate with allergic reaction severity, unlike histamine or tryptase. PAF was elevated in all severe anaphylaxis cases, highlighting its key role in allergic responses.

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