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Selected Reaction Monitoring Mass Spectrometry for Absolute Protein Quantification
09:04

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Quantitative mass spectrometry-based assay development and validation: from small molecules to proteins

Andrea Božović1, Vathany Kulasingam

  • 1Laboratory Medicine Program, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada M5G 2C4.

Clinical Biochemistry
|October 9, 2012
PubMed
Summary

Mass spectrometry (MS) is a powerful tool for analyzing biomolecules in clinical diagnostics. This review covers method development and validation for small molecules and proteins using liquid chromatography tandem mass spectrometry (LC-MS/MS).

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