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Topographical Estimation of Visual Population Receptive Fields by fMRI
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Ocular volumetry using fast high-resolution MRI during visual fixation.

K Tanitame1, T Sone, T Miyoshi

  • 1Department of Diagnostic Radiology, Graduate School of Biomedical Sciences, Hiroshima University, and Departmentof Clinical Radiology, Hiroshima University Hospital, Hiroshima, Japan. tntrad@msl.megaegg.ne.jp

AJNR. American Journal of Neuroradiology
|October 9, 2012
PubMed
Summary

Ocular MR volumetry using RARE sequences is reproducible and superior to FSPGR for evaluating intraocular lesions. This method aids in treatment decisions for patients with ocular tumors.

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Radiology

Background:

  • Ocular volumetry aids in assessing treatment response and prognosis for intraocular lesions.
  • Reproducibility of ocular Magnetic Resonance (MR) volumetry requires validation.

Purpose of the Study:

  • To determine the reproducibility of ocular MR volumetry.
  • To compare the accuracy of different MR sequences for ocular volumetry.

Main Methods:

  • Optimized Half-Fourier single-shot RARE and FSPGR sequences at 1.5T.
  • Compared sequence accuracy with phantom volumes.
  • Assessed intraobserver and interobserver reproducibility in 15 volunteers and utility in 6 patients with intraocular tumors.

Main Results:

  • RARE sequences showed significantly lower measurement error rates than FSPGR.
  • RARE volumetry demonstrated excellent imaging and intraobserver reproducibility for whole eyeballs and anterior chambers.
  • Follow-up volumetric data proved useful for treatment decisions in all patients.

Conclusions:

  • Ocular volumetry using ultrafast RARE images is feasible and reproducible in volunteers and patients.
  • This RARE imaging technique is superior to FSPGR for ocular volumetry.