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Graham-Little Piccardi Lassueur syndrome: case report
Raquel Bissacotti Steglich1, Renata Elise Tonoli, Giselle Martins Pinto
1Dermatology Service, Charity Hospital of Porto Alegre, RS, Brazil. raquelsteglich@yahoo.com.br
Anais Brasileiros De Dermatologia
|October 10, 2012
Summary
This case study highlights a rare disorder, Piccardi-Lassueur-Graham-Little syndrome, involving scalp alopecia and hair loss. Corticosteroid treatment showed improvement in a patient with this challenging condition.
Area of Science:
- Dermatology
- Pathology
Background:
- Piccardi-Lassueur-Graham-Little syndrome is a rare condition characterized by scarring alopecia, follicular keratosis, and hypotrichosis.
- Management of this syndrome is challenging, with varied treatment outcomes.
Observation:
- A 33-year-old woman presented with a 3-year history of progressive scalp alopecia, atrophic scalp changes, and hypotrichosis.
- Dermoscopy revealed hyperkeratosis and prominent follicular ostia.
- Histopathology showed reduced hair follicles, perifollicular inflammation, and fibrosis.
Findings:
- The patient's condition did not improve with hydroxychloroquine treatment.
- The case presented aligns with the diagnostic criteria for Piccardi-Lassueur-Graham-Little syndrome.
Implications:
- Corticosteroids may be an effective treatment option for Piccardi-Lassueur-Graham-Little syndrome.
- This case contributes to understanding the clinical presentation and potential management of this rare disorder.
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