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Molecular adaptations to concurrent training.
E O de Souza1, V Tricoli, H Roschel
1Department of Sport, School of Physical Education and Sport, University of São Paulo, SP, Brazil. desouza.eo@gmail.com
International Journal of Sports Medicine
|October 10, 2012
Summary
Concurrent training (CT) effectively enhances endurance and strength, matching strength training (ST) gains in muscle size and strength. Molecular adaptations varied, but CT did not impede hypertrophy or strength development.
Area of Science:
- Exercise physiology
- Molecular biology
- Sports science
Background:
- Concurrent training (CT) combines endurance and strength exercises.
- Understanding its effects on muscle adaptations is crucial for optimizing training programs.
Purpose of the Study:
- To investigate the chronic effects of CT on morphological and molecular adaptations.
- To compare CT with interval training (IT) and strength training (ST).
Main Methods:
- 37 men participated in an 8-week training program (CT, IT, ST, or control).
- Evaluated maximum strength (1RM), muscle cross-sectional area (CSA), and molecular markers (p70S6K1, Akt, AMPK).
Main Results:
- CT and IT improved VO2max and time to exhaustion compared to controls.
- ST and CT groups showed significant increases in 1RM and quadriceps CSA.
- Molecular adaptations differed: p70S6K1 increased in CT, Akt phosphorylation in ST, and AMPK phosphorylation in IT.
Conclusions:
- CT promotes significant strength and hypertrophy gains comparable to ST.
- Different training modes induce distinct molecular adaptations.
- CT is an effective training strategy without compromising muscle strength or size.
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