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Updated: May 17, 2026

07:34
The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions
Published on: February 16, 2017
Sea urchin embryos and larvae as biosensors for neurotoxicants
Gennady A Buznikov1, Theodore A Slotkin, Jean M Lauder
1N.K. Koltzov Institute of Developmental Biology, Moscow, Russia.
Current Protocols in Toxicology
|October 10, 2012
Abstract:
Sea urchin embryos and larvae provide an inexpensive high-throughput system for determining developmental actions of neuropharmacologic agents or environmental neurotoxins in both applied and basic biologic contexts. The use of this system for the testing of chlorpyrifos, 1-nicotine, lipophilic amides of choline, and ritanserin is described in detail.
