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Updated: May 17, 2026

Capillary Electrophoresis Mass Spectrometry Approaches for Characterization of the Protein and Metabolite Corona Acquired by Nanomaterials
Published on: October 27, 2020
Measured effects of various electrolyte and capillary properties in dielectric barrier electrospray ionization:
Irina Reginskaya1, Ann-Kathrin Stark, Michael Schilling
1Leibniz-Institut für Analytische Wissenschaften-ISAS-e.V., Otto-Hahn-Str. 6b, 44227 Dortmund, Germany.
Abstract:
The mechanism which leads to a dielectric barrier electrospray (DB-ES) was investigated by measurements of the electrical current. It comprises several components, namely, the displacement current, currents which are initiated by electromagnetic transmission, an ion current inside the capillary, which is responsible for the built-up of the potential at the tip, and the electrospray current as a result of the displacement current and the ion transfer current. An augmented interpretation of the current signal of the DB-ES is presented, and features are described in more detail. The behavior of the ions inside the capillary and the charge transfer are described from the chemical and the electrical point of view.
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