Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Suprachoroidal Triamcinolone Acetonide for the Treatment of Refractory Macular Edema Secondary to Non-Infectious Uveitis.

Pharmaceutics·2026
Same author

Toxoplasmosis meets the World Health Organization criteria for a neglected tropical disease.

PLoS neglected tropical diseases·2026
Same author

RWC Update: Modern One Health Approaches to Novel Challenges in Infectious Uveitis-Parasitic, Fungal and Mycobacterial Uveitis (Part 2); Management of 180° Iridodialysis With Aphakia and Total Hyphema; Retinal Astrocytic Hamartoma.

Ophthalmic surgery, lasers & imaging retina·2026
Same author

Comparative long-term outcomes of conventional immunomodulatory therapy, biologic agents, and combination therapy in chronic uveitis.

Journal of ophthalmic inflammation and infection·2026
Same author

RWC Update: Modern One Health Approaches to Novel Challenges in Infectious Uveitis-Emerging Viral Diseases (Part 1); Repair of Closed Funnel Retinal Detachment Through Boston KPro; Choroidal Rupture.

Ophthalmic surgery, lasers & imaging retina·2026
Same author

Molecular responses of human retinal pigment epithelial cells to ebolavirus VP24.

Molecular vision·2026
Same journal

Laser vision correction (LASIK, PRK, SMILE) with simultaneous accelerated corneal crosslinking.

Current opinion in ophthalmology·2026
Same journal

Traumatic macular hole: observe, operate, or other options.

Current opinion in ophthalmology·2026
Same journal

The evolving role of artificial intelligence in ophthalmology: basic science, translation, and clinical integration.

Current opinion in ophthalmology·2026
Same journal

Editorial: reducing risk for refractive surgery.

Current opinion in ophthalmology·2026
Same journal

Updates on Refractive Surgery: Benefits, Risks, and Costs of Modern Treatment Options.

Current opinion in ophthalmology·2026
Same journal

Corneal Allogeneic Intrastromal Ring Segments for keratoconus - recent evidence and the move to customized and custom shaped CAIRS.

Current opinion in ophthalmology·2026
See all related articles

Related Experiment Video

Updated: May 17, 2026

Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

Update on ocular tuberculosis.

Steven Yeh1, Hatice N Sen, Marcus Colyer

  • 1Division of Uveitis, Vitreoretinal Disease and Surgery, Department of Ophthalmology, Emory Eye Center, Emory University School of Medicine, Atlanta, Georgia, USA.

Current Opinion in Ophthalmology
|October 11, 2012
PubMed
Summary
This summary is machine-generated.

Diagnosing ocular tuberculosis is challenging. Quantitative PCR shows promise for identifying mycobacterial load in eye fluids, aiding diagnosis when combined with clinical signs.

Related Experiment Videos

Last Updated: May 17, 2026

Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis
10:33

Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis

Published on: December 17, 2021

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Microbiology

Background:

  • Tuberculosis (TB) remains a significant global health issue, despite recent declines.
  • Ocular involvement in TB presents diagnostic challenges.

Purpose of the Study:

  • To provide an updated review of demographic, clinical, experimental, and diagnostic data for ocular tuberculosis.
  • To highlight emerging diagnostic modalities and challenges in TB diagnosis.

Main Methods:

  • Review of recent literature on ocular tuberculosis.
  • Analysis of diagnostic techniques including quantitative PCR and interferon-γ release assays.
  • Examination of findings from porcine models of ocular tuberculosis.

Main Results:

  • Quantitative PCR for mycobacterial load in intraocular fluids shows potential for diagnosing ocular TB.
  • Porcine models offer insights into Mycobacterium tuberculosis infection of the choroid.
  • Distinguishing TB from sarcoidosis involves tuberculin skin tests, ocular surface disease, and vasculitis patterns.

Conclusions:

  • Diagnosing ocular tuberculosis remains difficult with current methods.
  • Interferon-γ release assays differentiate TB exposure but not latent vs. active TB.
  • Advancements in quantitative PCR could improve early diagnosis and treatment of ocular TB.