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Related Concept Videos

Short-distance Transport of Resources02:12

Short-distance Transport of Resources

Short-distance transport refers to transport that occurs over a distance of just 2-3 cells, crossing the plasma membrane in the process. Small uncharged molecules, such as oxygen, carbon dioxide, and water, can diffuse across the plasma membrane on their own. In contrast, ions and larger molecules require the assistance of transport proteins due to their charge or size. Transport across membranes also occurs within individual cells, playing a variety of essential roles for the plant as a whole.
Multicompartment Models: Overview01:14

Multicompartment Models: Overview

Multicompartment models are mathematical constructs that depict how drugs are distributed and eliminated within the body. They segment the body into several compartments, symbolizing various physiological or anatomical areas connected through drug transfer processes such as absorption, metabolism, distribution, and elimination.
These models offer a more comprehensive representation of drug behavior in the body than one-compartment models. They accommodate the complexity of drug distribution,...
Mechanistic Models: Compartment Models in Individual and Population Analysis01:23

Mechanistic Models: Compartment Models in Individual and Population Analysis

Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least squares (OLS)...
Mechanistic Models: Overview of Compartment Models01:21

Mechanistic Models: Overview of Compartment Models

Mechanistic models, a category encompassing both physiological and compartmental modeling, differ from empirical models' approaches to incorporating known factors about the systems being modeled. Empirical models describe data with minimal assumptions, while mechanistic models aim to provide a robust description of available data by specifying assumptions and integrating known factors about the system. Compartmental analysis is a key example of a mechanistic model in pharmacokinetics and...
Social Traps01:41

Social Traps

Social traps are negative situations where people get caught in a direction or relationship that later proves to be unpleasant, with no easy way to back out of or avoid. The concept was orignally introduced by John Platt who applied psychology to Garrett Hardin's "Tragedy of the Commons", where in New England herd owners could let their cattle graze in the common ground. This situation seems like a good idea, but an individual could have an advantage. If they owned more cows, the larger...
Three-Compartment Open Model01:06

Three-Compartment Open Model

The three-compartment open model is a pharmacokinetic model used to describe the distribution and elimination of drugs following extravascular administration. It comprises a central compartment representing the plasma and two peripheral compartments. The highly perfused peripheral compartment represents organs and tissues with a rich blood supply, such as the liver, kidneys, and lungs. The scarcely perfused peripheral compartment represents tissues with lower blood supply, such as adipose...

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Related Experiment Video

Updated: May 17, 2026

Modeling the Functional Network for Spatial Navigation in the Human Brain
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Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

A universal model of commuting networks.

Maxime Lenormand1, Sylvie Huet, Floriana Gargiulo

  • 1LISC, Irstea, Clermont-Ferrand, France. maxime.lenormand@irstea.fr

Plos One
|October 11, 2012
PubMed
Summary

A new model accurately predicts global commuting networks using origin-destination data. This model

Area of Science:

  • Urban studies
  • Network science
  • Computational social science

Background:

  • Commuting patterns are crucial for urban planning and economic activity.
  • Existing models for generating commuting networks face limitations in accuracy and universality.
  • Understanding inter-unit travel flows is essential for infrastructure development.

Purpose of the Study:

  • To introduce and validate a novel model for generating accurate commuting networks.
  • To demonstrate the model's effectiveness across diverse geographic scales and regions.
  • To compare the proposed model against existing universal commuting models.

Main Methods:

  • The model utilizes origin and destination commuter counts for each geographic unit.
  • It generates a matrix representing commuting flows between these units.

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Modeling the Functional Network for Spatial Navigation in the Human Brain
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Modeling the Functional Network for Spatial Navigation in the Human Brain

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Evaluating the Effect of Roadside Parking on a Dual-Direction Urban Street
14:55

Evaluating the Effect of Roadside Parking on a Dual-Direction Urban Street

Published on: January 20, 2023

  • A single, scale-dependent parameter governs the model's predictions.

    • Main Results:

    • The model accurately reproduces commuting networks in 80 diverse case studies.
    • Performance was validated across various scales, from municipalities to regions, in Europe and the United States.
    • The proposed model significantly outperforms two prior universal commuting models, especially at the municipal scale.

    Conclusions:

    • The developed model offers a robust and accurate method for simulating commuting networks.
    • Its universal parameter law simplifies application across different geographic contexts.
    • This approach provides a valuable tool for urban and transportation planning.