Related Experiment Video
Updated: May 17, 2026

Assessing Whole-Body Lipid-Handling Capacity in Mice
Published on: November 24, 2020
[Effect of different dietary protein source and protein level on serum lipids profile in rats]
Jia Luo1, Zhongqing Sun, Ling Yan
1Institute of Nutrition and Food Safety, China CDC, Beijing 100050, China. carejiajia@126.com
Objective:
The aim of this study was to evaluate the effect of dietary protein source and protein level on serum lipids in male rats.
Methods:
Wistar weaning male rats were assigned to four groups (15 rats in each group) according to their original body weight. The effects of two kinds of dietary protein with two different levels, including low cow milk (LM, 9%), high cow milk (HM, 18%), low soybean and egg white (LS, 9%), and high soybean and egg white (HS, 18%) diets, were observed. Each group was provided with one of four diets for 20 weeks. Serum lipids were tested and the ratio of lipid were calculated.
Results:
Serum TC and HDL-C were the highest and TC/HDL-C was the lowest in HM group; serum TG in HS group was the lowest. The ratio of TG/HDL-C in HS and HM group was lower than LS and LM group. Compared with LM and HM groups, serum LDL-C and LDL-C/HDL-C was lower in LS and HS group.
Conclusion:
Long-term intake of protein from soybean and egg white, serum TG level may be significantly lower, which may reduce the risk of atherosclerosis. There was a trend of rising serum cholesterol level in rats fed with protein from cow milk for a long time.
Related Concept Videos
Proteins: Dietary Sources and Requirements
Blood Studies for Cardiovascular System III: Serum Lipid Profile
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...

