Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Infertility in Males01:23

Infertility in Males

Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
Spermatogenesis01:41

Spermatogenesis

Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male reproductive...
Infertility in Females01:28

Infertility in Females

Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of endometrial...
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
The Y Chromosome Determines Maleness02:19

The Y Chromosome Determines Maleness

The Y chromosome is a sex chromosome found in several vertebrates and mammals, including humans. In addition to 22 pairs of autosomes, the human males have one X chromosome and one Y chromosome. In these organisms, the presence or absence of the Y chromosome determines the development of male traits.
Evolution
Around 300 million years ago, the two sex chromosomes diverged from two identical autosomal chromosomes. Over time, the Y chromosome has lost most of its genes, shrinking in size. Today,...
Sex-linked Disorders01:43

Sex-linked Disorders

Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

In utero and childhood exposure to organochlorines and perfluorinated chemicals in relation to sperm aneuploidy in adulthood.

Environmental health : a global access science source·2026
Same author

Use of antidepressants and assisted reproductive technology treatment outcomes: a Danish nationwide register-based cohort study.

Fertility and sterility·2026
Same author

Impact of adjuvant anti-PD-1 immunotherapy on ovarian function in female patients with resectable melanoma: A prospective observational study.

European journal of cancer (Oxford, England : 1990)·2026
Same author

Does Prolonged Preservation of Blastocysts Affect the Implantation and Live Birth Rate? A Danish Nationwide Register-Based Study.

Journal of clinical medicine·2026
Same author

Serum magnesium is linked with sperm concentration, motile sperm count and serum anti-Müllerian hormone in infertile men.

Reproductive biomedicine online·2026
Same author

High Seminal Fluid Calcium Is Associated With Higher Sperm Concentration in Infertile Men and Men From the General Population.

Andrology·2026
Same journal

[Mosaicism as a cause of Cowden syndrome].

Ugeskrift for laeger·2026
Same journal

[Thyrotoxic crisis with cardiogenic shock].

Ugeskrift for laeger·2026
Same journal

[Mindfulness-based cognitive therapy in the treatment of depression].

Ugeskrift for laeger·2026
Same journal

[Fitness].

Ugeskrift for laeger·2026
Same journal

[Risk of developing cataract related to fluoroscopy].

Ugeskrift for laeger·2026
Same journal

[Obturator hernia with small bowel ileus presenting as hip pain in an elderly woman].

Ugeskrift for laeger·2026
See all related articles

Related Experiment Video

Updated: May 17, 2026

Mouse Round Spermatid Injection
08:41

Mouse Round Spermatid Injection

Published on: January 26, 2024

[Male infertility].

Loa Nordkap1, Elisabeth Carlsen, Jens Fedder

  • 1Afdelingen for Vækst og Reproduktion, Rigshospitalet, Blegdamsvej 9, Copenhagen. Niels.Joergensen@regionh.dk

Ugeskrift for Laeger
|October 12, 2012
PubMed
Summary
This summary is machine-generated.

Male subfertility affects about 4% of newborn conceptions, with causes often unclear. Identifying the reasons for male infertility is crucial for diagnosing underlying health issues.

More Related Videos

High-Resolution Respirometry to Assess Mitochondrial Function in Human Spermatozoa
08:32

High-Resolution Respirometry to Assess Mitochondrial Function in Human Spermatozoa

Published on: June 23, 2023

Related Experiment Videos

Last Updated: May 17, 2026

Mouse Round Spermatid Injection
08:41

Mouse Round Spermatid Injection

Published on: January 26, 2024

High-Resolution Respirometry to Assess Mitochondrial Function in Human Spermatozoa
08:32

High-Resolution Respirometry to Assess Mitochondrial Function in Human Spermatozoa

Published on: June 23, 2023

Area of Science:

  • Reproductive Medicine
  • Andrology
  • Genetics

Context:

  • Infertility treatments are increasingly common, with 8% of Danish newborns conceived this way.
  • Male subfertility accounts for roughly half of all infertility cases.
  • A definitive cause for male infertility is identified in only about 50% of instances.

Purpose:

  • To highlight the significance of investigating male subfertility.
  • To emphasize the diagnostic challenges in male infertility.
  • To underscore the potential systemic health implications of low semen quality.

Summary:

  • Male subfertility is a significant factor in assisted reproductive technology outcomes.
  • The etiological basis of male infertility remains elusive in many cases.
  • Low semen quality can be an indicator of serious underlying conditions such as pituitary dysfunction, genetic abnormalities, or testicular cancer.

Impact:

  • Improved diagnostic approaches for male infertility.
  • Earlier detection of potential systemic diseases linked to male subfertility.
  • Enhanced understanding of the multifactorial nature of male reproductive health.