Related Experiment Video
Updated: May 17, 2026

10:32
Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts
Published on: March 26, 2015
Arthroscopic single-bundle ACL reconstruction with modified double-layer bone-patellar tendon-bone allograft.
Hui Jun Kang1, Yan Ling Su, Hui Jian Cao
1Department of Orthopaedic Surgery, Shijiazhuang No. 1 Hospital, Shijiazhuang, 050011, Hebei, China.
Summary
A modified double-layer bone-patellar tendon-bone (BPTB) allograft for ACL reconstruction resulted in less anterior laxity and improved knee function compared to single-layer grafts. This technique enhances outcomes for patients undergoing anterior cruciate ligament repair.
Area of Science:
- Orthopedic surgery
- Sports medicine
- Biomedical engineering
Background:
- Anterior cruciate ligament (ACL) reconstruction is a common orthopedic procedure.
- Bone-patellar tendon-bone (BPTB) autografts and allografts are widely used.
- Improving graft stability and clinical outcomes remains an area of research.
Purpose of the Study:
- To introduce a modified double-layer BPTB allograft for arthroscopic single-bundle ACL reconstruction.
- To investigate and compare the clinical outcomes of the modified double-layer allograft versus conventional single-layer BPTB allograft.
Main Methods:
- A retrospective comparative study involving 136 patients undergoing arthroscopic single-bundle ACL reconstruction.
- Patients were divided into two groups: 66 with double-layer BPTB allograft (Group 1) and 70 with conventional BPTB allograft (Group 2).
- Clinical outcomes were assessed at a minimum 2-year follow-up using Lachman tests, pivot-shift tests, KT-1000 arthrometer measurements, and Lysholm and Tegner activity scores.
Main Results:
- At a minimum 2-year follow-up, the double-layer allograft group (Group 1) showed significantly less anterior laxity (mean side-to-side difference on KT-1000: 1.2 mm vs 2.1 mm, p=0.017).
- Knee function was significantly better in Group 1, with higher Lysholm scores (94.2 vs 86.6, p=0.000) and Tegner scores (median 8 vs 6, p=0.001).
Conclusions:
- The modified double-layer BPTB allograft technique leads to significantly reduced anterior laxity in single-bundle ACL reconstruction.
- This modified allograft approach demonstrates superior knee function compared to conventional single-layer BPTB allografts.
- The study supports the use of double-layer BPTB allografts for improved outcomes in ACL reconstruction.