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Updated: May 17, 2026
Tissue-simulating Phantoms for Assessing Potential Near-infrared Fluorescence Imaging Applications in Breast Cancer Surgery
Published on: September 19, 2014
Real-time pathology to guide breast surgery: seeing alone is not believing
1Department of Biomedical Engineering, Electrical & Computer Engineering, and Medicine, Boston University, Boston, Massachusetts 02215, USA. bigio@bu.edu
Abstract:
Tissue diagnostic techniques based on optical spectroscopy, in various incarnations, are approaching clinical reality for intraoperative guidance of surgical procedures. Examination of tissue properties by elastic light-scattering spectroscopy may constitute a preferable alternative to frozen-section pathology or touch imprint cytology for intraoperative assessment of resection margins during breast-conserving surgery.
