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Related Experiment Video

Updated: May 17, 2026

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers

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FluoSTIC: miniaturized fluorescence image-guided surgery system.

Sylvain Gioux¹, Jean-Guillaume Coutard, Michel Berger

¹Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA. sgioux@bidmc.harvard.edu

Journal of Biomedical Optics

|October 12, 2012

Summary

This summary is machine-generated.

A new miniaturized near-infrared (NIR) fluorescence imaging system, FluoSTIC, is developed for head and neck cancer surgeries. This low-cost device offers high-quality imaging in deep cavities, improving surgical precision.

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Area of Science:

Medical Imaging
Surgical Oncology
Biomedical Engineering

Background:

Near-infrared (NIR) fluorescence imaging is increasingly used in clinical settings.
Current NIR systems are often large, limiting their use in confined surgical spaces like head and neck procedures.
Existing systems struggle with imaging deep cavities and surgeon access during oncologic surgeries.

Purpose of the Study:

To develop a miniaturized, cost-effective NIR fluorescence imaging system for oral oncologic surgeries.
To overcome the limitations of large imaging systems in head and neck cancer procedures.
To provide surgeons with improved visualization within deep surgical cavities.

Main Methods:

Development of a compact NIR fluorescence system named FluoSTIC.
Utilized a miniature, consumer-grade lipstick camera for fluorescence light collection.
Incorporated a custom circular optical fiber array for combined white light and NIR excitation.

Main Results:

The FluoSTIC system maintains fluorescence imaging quality comparable to larger systems.
The device features a small footprint (22 mm diameter, 200 mm height) and low weight (<200 g).
Optimized for clinical use in oral oncologic surgeries, enabling imaging in deep cavities.

Conclusions:

The miniaturized FluoSTIC system is suitable for head and neck oncologic surgeries.
This technology enhances visualization in deep cavities, addressing limitations of current systems.
Offers a low-cost, high-quality solution for intraoperative fluorescence imaging in specialized surgical fields.