Related Experiment Video
Updated: May 17, 2026

04:16
Intraoperative Visualization of Subretinal Injection and Retinal Detachment in Rats
Published on: March 7, 2025
[Conspicuous crystalline lens foreign body after intravitreal injection]
Summary
A rare case of Ozurdex® injection misplaced into the crystalline lens occurred. Subsequent cataract surgery was successful due to capsular fibrosis, enabling uncomplicated intraocular lens fixation.
Area of Science:
- Ophthalmology
- Retinal Vascular Diseases
- Cataract Surgery
Background:
- Retinal branch vein occlusion and macular edema are common causes of vision loss.
- Ozurdex® (dexamethasone intravitreal implant) is a treatment for macular edema.
- Intraocular foreign bodies can lead to severe complications.
Observation:
- A 63-year-old woman presented with a misplaced Ozurdex® implant within the crystalline lens.
- Recurrent macular edema necessitated multiple Ozurdex® reinjections.
- Advanced cataract formation occurred 11 months after initial presentation.
Findings:
- The inadvertent intraocular placement of Ozurdex® into the lens was diagnosed.
- Phacoemulsification was performed for cataract removal.
- Fibrosis of the capsular defect facilitated uncomplicated intraocular lens (IOL) fixation into the capsular bag.
Implications:
- This case highlights a rare complication of intravitreal injections.
- Capsular fibrosis can positively influence surgical outcomes in complex cases.
- Careful surgical technique is crucial for managing intraocular lens implantation after complicated procedures.
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