Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Lymphatic Vessels and Lymph Transport01:16

Lymphatic Vessels and Lymph Transport

Lymphatic vessels, known as lymphatics, are crucial in transporting lymph from peripheral tissues to our venous system. This process begins with lymph entering through tiny capillaries that branch through tissues. These capillaries have unique features such as larger diameters, thinner walls, and a distinctive one-way valve system formed by overlapping endothelial cells.
This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular spaces.
Overview of the Vascular System01:20

Overview of the Vascular System

The vascular system comprises an extensive network of arteries, capillaries, and veins. The vascular system can be broadly divided into the blood and lymphatic systems. Typically, blood vessels can be categorized into three histological regions: tunica intima, tunica media, and tunica adventitia. The tunica intima consists of a single layer of endothelial cells attached to the basal lamina. Underlying the basal lamina is a connective tissue layer and an elastic lamina that gives stability and...
Functions of the Lymphatic and Immune System01:28

Functions of the Lymphatic and Immune System

The lymphatic system plays a crucial role in bolstering our immune system. It consists of a network of lymphoid organs, lymph, and lymphatic vessels that provide structural and functional support in safeguarding the body against pathogens such as viruses and bacteria.
The primary lymphoid organs, including the bone marrow and the thymus, serve as the maturation sites for lymphocytes. Secondary lymphoid organs, like the mucosa-associated lymphoid tissue, activate these lymphocytes and serve as...
Development of the Lymphatic System01:15

Development of the Lymphatic System

The development of lymphatic tissues and vessels in embryonic life begins around the fifth week. These structures originate from the mesoderm layer, with lymph sacs emerging from developing veins.
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
Detailed Structure and Function of Lymph Nodes01:23

Detailed Structure and Function of Lymph Nodes

Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
Histology of the Uterus01:19

Histology of the Uterus

The uterine wall consists of three histological layers: the perimetrium, myometrium, and endometrium. The outermost perimetrium is a thin, serous membrane connected with the broad ligament on the sides, which helps anchor the uterus in the pelvic cavity. The thickest layer, myometrium, is mainly made up of smooth muscle tissue bundles. Its contractions are vital in facilitating the expulsion of the uterine lining, fetus, and placenta during menstruation and childbirth.
The endometrium is the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Proteomic Analysis of Cervicovaginal Fluid for Diagnostic Endometriosis Biomarker Discovery.

Proteomics. Clinical applications·2026
Same author

Modelling menstruation in the common mouse: a narrative review.

Reproduction, fertility, and development·2025
Same author

Regulation of RNA splicing in endometrial tissue and its association with endometriosis.

iScience·2025
Same author

Supportive Care Needs of Young Adults With Endometriosis: An Open-Ended Online Survey and Exploration of Unmet Needs.

Health expectations : an international journal of public participation in health care and health policy·2024
Same author

Predicting disease recurrence in patients with endometriosis: an observational study.

BMC medicine·2024
Same author

Positron emission tomography in the evaluation of endometriosis: A systematic review.

European journal of obstetrics, gynecology, and reproductive biology·2024

Related Experiment Video

Updated: May 17, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
07:36

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

The endometrial lymphatic vasculature: function and dysfunction.

Jane E Girling1, Peter A W Rogers

  • 1Gynaecology Research Centre, Department of Obstetrics and Gynaecology, The University of Melbourne, The Royal Women's Hospital, Cnr Flemington Rd and Grattan St, Parkville, VIC, Australia. jgirling@unimelb.edu.au

Reviews in Endocrine & Metabolic Disorders
|October 12, 2012
PubMed
Summary
This summary is machine-generated.

Endometrial lymphatic vessels have a limited distribution, and their function and role in disorders remain unclear. Further research is needed to understand these crucial lymphatic pathways.

More Related Videos

Murine Dermal Lymphatic Endothelial Cell Isolation
05:52

Murine Dermal Lymphatic Endothelial Cell Isolation

Published on: July 21, 2023

Related Experiment Videos

Last Updated: May 17, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
07:36

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

Murine Dermal Lymphatic Endothelial Cell Isolation
05:52

Murine Dermal Lymphatic Endothelial Cell Isolation

Published on: July 21, 2023

Area of Science:

  • Reproductive biology
  • Vascular biology
  • Gynecology

Background:

  • The endometrium possesses intricate blood and lymphatic vasculature that cycles regularly.
  • Endometrial blood vasculature is well-understood, but lymphatic vasculature remains largely unexplored.
  • Recent findings show a restricted distribution of lymphatic vessels in the functional layer of the endometrium.

Purpose of the Study:

  • To review the current knowledge of endometrial lymphatic vessels.
  • To explore mechanisms regulating lymphatic vessel growth and function.
  • To discuss the role of lymphatics in endometrial disorders.

Main Methods:

  • Literature review of existing studies on endometrial lymphatics.
  • Synthesis of current understanding of lymphatic vessel biology.
  • Discussion of potential links to gynecological conditions.

Main Results:

  • Endometrial lymphatics exhibit a restricted distribution, particularly in the functional layer.
  • Mechanisms and functional consequences of this distribution are currently unknown.
  • The review consolidates existing data and highlights knowledge gaps.

Conclusions:

  • Understanding endometrial lymphatic vessel distribution and function is critical.
  • Lymphatics may play a significant role in endometrial health and disease.
  • Further investigation into lymphangiogenesis and lymphatic function is warranted.