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Related Concept Videos

Intestinal Obstruction I: Introduction01:29

Intestinal Obstruction I: Introduction

Intestinal obstruction is a partial or complete blockage of the small or large intestine that disrupts the normal flow of intestinal contents through the lumen. This interruption impairs digestion, absorption, and fluid balance, and may lead to serious complications if not treated promptly.Mechanical ObstructionMechanical obstruction occurs when a physical blockage prevents intestinal contents from passing, arising from within the lumen or the bowel wall, or from external compression.Adhesions,...
Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...

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Related Experiment Video

Updated: May 17, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis
08:49

Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

Severe adhesive small bowel obstruction.

Salomone Di Saverio1, Fausto Catena, Michael D Kelly

  • 1Emergency Surgery Unit, Department of General and Transplant Surgery, S. Orsola Malpighi University Hospital, Bologna, Italy. salo75@inwind.it

Frontiers of Medicine
|October 12, 2012
PubMed
Summary
This summary is machine-generated.

Adhesive small bowel obstruction can be managed non-operatively using water-soluble contrast, but surgery is vital if ischemia is suspected. Adhesion prevention strategies like icodextrin show promise for reducing recurrence.

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Creation of Abdominal Adhesions in Mice
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Creation of Abdominal Adhesions in Mice

Published on: August 27, 2016

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Last Updated: May 17, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis
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Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

Creation of Abdominal Adhesions in Mice
06:44

Creation of Abdominal Adhesions in Mice

Published on: August 27, 2016

Area of Science:

  • Gastroenterology
  • Surgical Innovation
  • Medical Technology

Background:

  • Adhesive small bowel obstruction (ASBO) frequently necessitates hospital admission.
  • Previous surgeries, particularly multiple laparotomies, increase the risk of ASBO.
  • Early diagnosis and management are crucial to prevent complications.

Observation:

  • A 58-year-old patient with extensive ASBO post-colorectal surgery experienced a complex clinical course.
  • Management involved non-operative strategies with hyperosmolar contrast, surgical interventions, parenteral nutrition, and icodextrin.
  • The patient achieved a 2-year symptom-free follow-up.

Findings:

  • Water-soluble contrast studies offer diagnostic and therapeutic benefits in ASBO, potentially avoiding surgery.
  • Recurrence risk escalates with prior episodes of ASBO.
  • Icodextrin, an anti-adhesion solution, may reduce the incidence of adhesions and subsequent obstruction.

Implications:

  • Non-operative management with water-soluble contrast is a viable strategy for select ASBO cases.
  • Prompt surgical intervention remains mandatory for suspected bowel ischemia.
  • Adhesion prevention research, including agents like hyaluronic acid-carboxycellulose and icodextrin, is critical for improving patient outcomes and reducing healthcare burden.