Related Experiment Video
Updated: Jan 25, 2026

Author Spotlight: A Novel 3D-Printed Titanium Implant for Minimally Invasive Treatment of Hip Dysplasia in Young Dogs
Published on: April 19, 2024
Constrained total hip megaprosthesis for primary periacetabular tumors
Takafumi Ueda1, Shigeki Kakunaga, Satoshi Takenaka
1Osaka University Orthopaedic Oncology Group, Osaka, Japan, uedat@onh.go.jp.
Limb-salvage surgery for periacetabular tumors using a constrained total hip mechanism (C-THA) shows potential for patient survival and function. Despite complications, C-THA offers a viable reconstructive option for these challenging oncologic cases.
Area of Science:
- Orthopaedic Oncology
- Surgical Reconstruction
- Tumor Surgery
Background:
- Periacetabular malignant tumors present significant reconstructive challenges in orthopaedic oncology.
- Existing reconstructive options lack standardization due to disease rarity and variability.
- A constrained total hip mechanism (C-THA) megaprosthesis was previously developed for this purpose.
Purpose of the Study:
- To evaluate patient survival and C-THA implant survival.
- To assess postoperative functional outcomes.
- To identify and analyze postoperative complications.
Main Methods:
- Retrospective review of 25 patients with primary periacetabular tumors treated with C-THA (1985-2009).
- Analysis of patient demographics, tumor types, surgical margins, and follow-up duration.
- Evaluation of survival rates, functional status, and complication incidence.
Main Results:
- The 10-year overall survival rate was 47%; C-THA implants survived in 19 of 25 patients.
- Twenty-one patients achieved ambulatory activity post-surgery.
- Complications included deep infection (8/25), dislocation (4/25), and aseptic loosening (2/25), requiring revision surgeries.
Conclusions:
- Constrained total hip mechanism (C-THA) with an acetabular reconstruction cup is a useful option for periacetabular malignant tumor resection.
- The procedure offers a viable reconstructive solution despite a notable rate of postoperative complications.
- Further research may focus on mitigating complications associated with C-THA in this patient population.
Related Concept Videos
Total Voids in Concrete
Total Internal Reflection Fluorescence Microscopy
Primary Active Transport
Static, Stagnation, Dynamic and Total Pressure
Primary and Secondary Growth in Roots and Shoots
Primary Distribution

