Retinopathy of prematurity in infants with late retinal examination

S Zeinab Mousavi1, Reza Karkhaneh, Mohammad Riazi-Esfahani

  • 1Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Insights

Late screening for retinopathy of prematurity (ROP) in premature infants revealed a high incidence of severe ROP. Timely ROP examinations are crucial for preventing vision loss in vulnerable newborns.

Area of Science:

  • Ophthalmology
  • Neonatology
  • Public Health

Background:

  • Retinopathy of prematurity (ROP) is a significant cause of vision impairment in premature infants.
  • Delayed screening for ROP can lead to advanced disease and irreversible vision loss.
  • Understanding risk factors and incidence is crucial for effective ROP management.

Purpose of the Study:

  • To determine the incidence and severity of ROP in premature infants.
  • To identify risk factors associated with ROP development.
  • To evaluate ROP outcomes in infants with late screening at Farabi Eye Hospital.

Main Methods:

  • Retrospective review of hospital records for premature infants screened for ROP.
  • Data collected from January 2001 to July 2007.
  • Analysis included infant demographics, gestational age, birth weight, and various medical interventions.

Main Results:

  • 27.1% of infants had late ROP examinations (mean age 141.7 days).
  • 40.3% of these infants presented with ROP, with 16.2% having untreatable stage 5 ROP.
  • Lower gestational age, respiratory distress syndrome, and blood transfusion were linked to ROP development.

Conclusions:

  • The prevalence of ROP, especially severe ROP, is high with delayed screening.
  • Urgent interventions are needed to ensure timely ROP screening for premature infants.
  • Optimizing referral pathways can improve ROP outcomes and prevent severe visual impairment.
Abstract