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Comparing Oral Route Paraffin Oil versus Rectal Route for Disimpaction in Children with Chronic Constipation; a
Fatemeh Farahmand1, Kambiz Eftekhari, Vajiheh Modarresi
1Department of Pediatrics, Faculty of medicine, Tehran University of Medical Sciences, Tehran, IR Iran ; Pediatrics Center of Excellence, Children's Medical Center, Tehran, IR Iran.
Insights
Oral paraffin oil is a preferred method for fecal disimpaction in children with functional constipation, showing higher family compliance and satisfaction compared to rectal administration. This approach reduces anxiety for families undergoing treatment.
Area of Science:
- Pediatric Gastroenterology
- Pharmacological Interventions
- Clinical Trial Design
Background:
- Functional constipation is a prevalent pediatric issue requiring effective fecal disimpaction before maintenance therapy.
- Current treatment guidelines recommend disimpaction for successful management of pediatric functional constipation.
Purpose of the Study:
- To compare the efficacy and patient compliance of oral versus rectal paraffin oil administration for fecal disimpaction in children.
- To evaluate family satisfaction and identify side effects associated with each administration route.
Main Methods:
- Eighty children (aged 1-12 years) with functional constipation and fecal impaction were randomized into two groups.
- Group I received oral paraffin oil (3 ml/kg/day), and Group II received rectal paraffin oil (3 ml/kg/day) for three consecutive days.
- Treatment success was defined by the absence of fecal impaction after 72 hours; compliance and satisfaction were assessed via questionnaires.
Main Results:
- Both oral and rectal paraffin oil showed high efficacy rates (92.5% vs 82.5%), with no significant difference.
- Family compliance and satisfaction were significantly higher with the oral route (87.5%) compared to the rectal route (57.5%).
- Anal oil seepage was the most common side effect (27.5%); nausea and abdominal pain were more frequent in the oral and rectal groups, respectively.
Conclusions:
- Oral administration of paraffin oil appears to be a preferred method for fecal disimpaction in children due to improved family compliance and satisfaction.
- The oral route may cause less anxiety for families compared to the rectal administration of paraffin oil for pediatric constipation treatment.
Objective:
Functional constipation is a common and challenging problem in pediatrics. Fecal disimpaction prior to maintenance therapy is recommended to ensure successful treatment. The aim of this study was to compare the efficacy and patient's compliance of the two methods of paraffin oil administration (oral and rectal route) with the purpose of disimpaction in treatment of children with functional constipation.
Methods:
A total of 80 children (49 males and 31 females) aged 1-12 years, with functional constipation according to Rome III criteria, whose rectal examination confirmed fecal impaction were divided into two groups randomly. Group I received 3 ml/kg/day paraffin oil orally and group II received 3ml/kg/day paraffin oil rectally during 3 consequent days. Successful treatment was defined as no detectable fecal impaction in rectal examination after at most 72 hours. Patient compliance and family satisfaction also was evaluated using a scored questionnaire.
Findings:
Response to the treatment in both groups was with 92.5% and 82.5% in group I and II, respectively. So, there was no significant difference between the two methods of therapy. Family satisfying and compliance were obviously more achieved in group 1 (87.5% vs 57.5%) than in Group 2 (P<0.001). No parents in group I complained about type of treatment while 12.5% of parents in group II were unsatisfied with the mode of paraffin oil administration. The most common side effect of paraffin oil in both groups was anal oil seepage (27.5%). Nausea and abdominal pain were more common side effects in group 1 and 2 respectively.
Conclusion:
It seems that using paraffin oil per oral route in comparison with rectal route could be a preferred option for disimpaction in children causing less anxiety to the family.
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