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Breastfeeding and helicobacter pylori infection in children with digestive symptoms

Maryam Monajemzadeh1, Fatemeh Farahmand, Fatemeh Vakilian

  • 1Department of Pathology, Tehran University of Medical Sciences, Tehran, IR Iran.

Iranian Journal of Pediatrics
|October 12, 2012
PubMed

Insights

Breastfeeding in the first six months can reduce Helicobacter pylori (H. pylori) colonization and symptom duration in children. This practice may also delay H. pylori infection and lead to milder gastritis.

Area of Science:

  • Pediatric Infectious Diseases
  • Gastroenterology
  • Microbiology

Background:

  • Helicobacter pylori (H. pylori) infection is a significant global health concern in children.
  • Understanding transmission routes, such as infant feeding practices, is crucial for prevention strategies.

Purpose of the Study:

  • To investigate the association between breastfeeding and H. pylori acquisition in Iranian children.
  • To compare histopathologic findings in breastfed versus formula-fed infants.

Main Methods:

  • A case-control study involving 154 children (77 cases, 77 controls) with and without H. pylori infection.
  • Data collected via parental questionnaires on feeding practices, symptom duration, and medical history.
  • Endoscopic surveys and gastric biopsies were performed.

Main Results:

  • Formula feeding showed a significant association with H. pylori infection (P=0.045).
  • Breastfeeding correlated with older age at infection (P=0.034), shorter symptom duration (P=0.016), and reduced H. pylori colonization degree (P=0.021).

Conclusions:

  • Early breastfeeding (first 6 months) appears to reduce H. pylori colonization intensity.
  • Breastfeeding may delay the age of H. pylori infection and shorten symptom duration.
  • Breastfeeding is associated with less severe gastritis in H. pylori-infected children.
Abstract

Keywords:
BreastfeedingFormulaGastritisHelicopter pylori

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