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Distribution of retinopathy of prematurity and its risk factors
Amirkhosro Ghaseminejad1, Pedram Niknafs
1Department of Ophthalmology, Kerman University of Medical Sciences, Kerman, Iran.
Insights
Retinopathy of prematurity (ROP) affects 29% of premature infants in Kerman, Iran. Lower gestational age and birth weight are key risk factors for ROP development.
Area of Science:
- Ophthalmology
- Neonatology
- Public Health
Background:
- Retinopathy of prematurity (ROP) is a significant cause of visual impairment in premature infants.
- Understanding ROP distribution and risk factors is crucial for early intervention.
Purpose of the Study:
- To determine the prevalence and risk factors of ROP in premature infants.
- To gather initial data on ROP in Kerman, Iran.
Main Methods:
- A prospective, cross-sectional study was conducted from 2006-2008.
- Data on premature infants in the Neonatal Intensive Care Unit (NICU) were collected, including risk factors and eye examination results.
- Statistical analysis included logistic regression and chi-square tests.
Main Results:
- 29% of 83 premature infants screened had ROP.
- Infants with ROP had a mean gestational age of 30.17 weeks and mean birth weight of 1247.92 grams.
- Gestational age and birth weight were significantly associated with ROP (P<0.001).
- Treatment was indicated for 25% of infants with ROP.
Conclusions:
- The study found a relatively high prevalence of ROP in the studied population.
- Gestational age and birth weight were identified as independent determinants of ROP.
Objective:
This study was conducted to determine the distribution and risk factors of retinopathy of prematurity (ROP) in premature infants referred to neonates intensive care unit (NICU) of central hospital of Kerman University of Medical Sciences, to obtain primary information on ROP in Kerman, Iran.
Methods:
In a cross sectional prospective study, data of premature infants screened for ROP including possible risk factors and eye examination results were recorded during 2006-2008 and analyzed by using logistic regression and chi-square tests.
Findings:
Out of 83 premature infants, 24 (29%) had different stages of ROP (CI 95%: 0.19-0.39). The infants' mean gestational age (GA) and mean birth weight (BW) in ROP group were 30.17±1.8 weeks and 1247.92±237.1 grams (g), respectively. Logistic regression analysis showed a significant relation between GA and BW with ROP (P<0.001). Indication for treatment was set in 6 (25%) infants.
Conclusion:
The results of this study illustrate a relatively high prevalence of ROP in this series. GA and BW were independent ROP determinants.
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