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OCD behavior therapy before and after gamma ventral capsulotomy: case report
Christopher M Spofford1, Nicole C R McLaughlin, Fred Penzel
1a Department of Psychiatry and Human Behavior , The Warren Alpert Medical School at Brown University , Providence , RI , USA.
Abstract:
We report the case of a patient requiring gamma ventral capsulotomy (GVC), a neurosurgical intervention to address severe refractory obsessive-compulsive disorder (OCD). GVC involves stereotactic lesions in the ventral anterior limb of the internal capsule and adjacent ventral striatum. This study details the course of an extinction-based behavioral therapy, namely exposure and response prevention (ERP). The patient experienced significant changes in motivation and ability to tolerate ERP post-surgery. Furthermore, he was better able to absorb and remember exposure sessions. GVC surgery may affect the neural mechanisms involved in the extinction learning process, the same process implicated in ERP treatment.
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