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Updated: May 17, 2026

Retroductal Nanoparticle Injection to the Murine Submandibular Gland

Retroductal Nanoparticle Injection to the Murine Submandibular Gland

Published on: May 3, 2018

Sublingual drug dispensing prosthesis.

Dhanraj Ganapthy¹, Padma Ariga, Anand Selvaraj

¹Department of Prosthodontics, Saveetha Dental College, Chennai, India.

Indian Journal of Dental Research : Official Publication of Indian Society for Dental Research

|October 13, 2012

Summary

This summary is machine-generated.

Sublingual drug delivery faces challenges when patients cannot retain tablets. A novel intra-oral prosthesis offers a solution by securely housing sublingual medications, improving drug efficacy and patient health outcomes.

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Area of Science:

Pharmaceutical Sciences
Biomedical Engineering
Dental Technology

Background:

Sublingual drug administration offers rapid and predictable delivery.
Certain patient groups struggle to retain sublingual tablets due to medical or psychological issues.
Swallowing or chewing sublingual tablets compromises medication efficacy.

Purpose of the Study:

To introduce a novel sublingual drug dispensing prosthesis.
To address challenges in sublingual tablet retention for specific patient populations.
To enhance the effectiveness of sublingual drug delivery.

Main Methods:

Development of a specialized intra-oral appliance.
Integration of custom slots within the prosthesis for sublingual tablet housing.
Evaluation of the prosthesis's ability to secure and facilitate sublingual medication delivery.

Main Results:

The sublingual drug dispensing prosthesis effectively retains tablets intra-orally.
The appliance facilitates consistent and intended sublingual drug absorption.
Improved patient compliance and therapeutic outcomes are anticipated.

Conclusions:

The sublingual drug dispensing prosthesis is a viable solution for patients with retention difficulties.
This innovation can significantly improve the efficacy of sublingual medications.
The device holds potential for enhancing patient health through improved drug delivery.