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Updated: May 17, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
Latin American algorithm for treatment of relapsing-remitting multiple sclerosis using disease-modifying agents
Alessandro Finkelsztejn1, Alberto Alain Gabbai, Yara Dadalti Fragoso
1Department of Neurology, Hospital de Clínicas de Porto Alegre, Porto Alegre RS, Brazil. alessandro.finkels@gmail.com
Objective:
It is estimated that circa 50,000 individuals have relapsing-remitting multiple sclerosis in Latin America. European and North-American algorithms for the treatment of multiple sclerosis do not foresee our regional difficulties and the access of patients to treatment.
Methods:
The Latin American Multiple Sclerosis Forum is an independent and supra-institutional group of experts that has assessed the latest scientific evidence regarding efficacy and safety of disease-modifying treatments. Accesses to treatment and pharmacovigilance programs for each of the eight countries represented at the Forum were also analyzed.
Results:
A specific set of guidelines based upon evidence-based recommendations was designed for Latin America. Future perspectives of multiple sclerosis treatment were also discussed.
Conclusions:
The present paper translated an effort from representatives of eight countries discussing a matter that cannot be adapted to our region directly from purely European and North-American guidelines for treatment.
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