Related Experiment Video
Updated: May 17, 2026
06:31
Transuterine Fetal Tracheal Occlusion Model in Mice
Published on: February 5, 2021
Bilateral congenital diaphragmatic hernia
Anjan Kumar Dhua1, Satish K Aggarwal, Nb Mathur
1Department of Pediatric surgery, Maulana Azad Medical College, Delhi 110002.
APSP Journal of Case Reports
|October 13, 2012
Summary
Bilateral congenital diaphragmatic hernia (CDH) is a rare defect. This case highlights the challenges in diagnosis and management, with the infant succumbing to pulmonary hypertension post-surgery.
Area of Science:
- Pediatric Surgery
- Neonatal Medicine
- Congenital Malformations
Background:
- Congenital diaphragmatic hernia (CDH) is a rare condition with significant mortality.
- Bilateral CDH presents unique diagnostic and therapeutic challenges.
Observation:
- A case of bilateral CDH was identified during surgical repair of a right-sided defect.
- Surgical intervention involved diaphragmatic defect repair and abdominal silo placement to prevent compartment syndrome.
Findings:
- The infant developed severe postoperative pulmonary hypertension.
- Despite surgical repair, the patient did not survive due to pulmonary complications.
Implications:
- This case underscores the critical need for early diagnosis and management strategies for bilateral CDH.
- Pulmonary hypertension remains a major challenge in CDH patient outcomes.
- Further research into managing severe pulmonary hypertension in neonates with CDH is warranted.
Related Concept Videos
01:25Hiatal Hernia
A hiatal hernia is the abnormal protrusion of the stomach or other abdominal organs through the esophageal hiatus of the diaphragm into the thoracic cavity.Normally, the gastroesophageal junction (GEJ) lies below the diaphragm and is supported by the phrenoesophageal membrane, the diaphragmatic crura, and connective tissues. Weakening of these structures—due to aging, congenital defects like a short esophagus, or increased intra-abdominal pressure from coughing, obesity, pregnancy, or heavy...
01:17Pulmonary Cycle: Exhalation
In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
01:08Pneumothorax II: Pathophysiology
Pneumothorax means the presence of air in the pleural space — the thin potential gap between the visceral and parietal pleura. This condition disrupts the normal pressure balance that keeps the lungs inflated, leading to partial or complete collapse of the affected lung.Normal physiologyUnder normal conditions, the pleural space maintains a slightly negative intrapleural pressure, which keeps the lungs expanded against the chest wall. This negative pressure creates a delicate balance between...
01:27Mitral Valve Prolapse I: Introduction
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...