Related Experiment Video
Updated: May 17, 2026

Isolation, Characterization and Functional Examination of the Gingival Immune Cell Network
Published on: February 16, 2016
Necrotizing periodontitis as a possible manifestation of common variable immunodeficiency
D Dalla Torre1, D Burtscher, S Jank
1Department of Cranio-, Maxillofacial and Oral Surgery, Medical University of Innsbruck, Innsbruck, Austria. daniel.dalla-torre@uki.at
Abstract:
Common variable immunodeficiency (CVID) is an inherited disease characterized by hypogammaglobulinaemia and impaired humoural immunoresponse and is mainly associated with recurrent infections of the airway and the digestive tract. An 18-year old female with a diagnosis of CVID associated with a devastating necrotizing periodontitis, ultimately resulting in complete destruction of the periodontium and loss of all teeth, is reported. Clinical, biochemical, microbiological and radiographic examinations are presented. The report highlights the likely importance of immunoglobulin replacement and intensive dental hygiene in CVID patients, and the devastating effect of non-compliance in such patients.
Related Concept Videos
Immunodeficiency Diseases
There are three main causes of immunodeficiency disorders...
Endocarditis II: Clinical Features of Infective Endocarditis
Cytomegalovirus Disease
Peptic Ulcer Disease III: Clinical Manifestations and Complications
Inflammatory Bowel Disease IV: Clinical Manifestations
Infectious Diseases and Their Occurrence
