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Bone mass in young patients with type I diabetes
G Weber1, L Beccaria, M de'Angelis
1Instituto Scientifico H San Raffaele, Clinica Pediatrica III, Milano, Italy.
Bone and Mineral
|January 1, 1990
Summary
Type I diabetes can affect bone mineral content (BMC) in young patients. While some show low BMC at diagnosis, most normalize within three years, though some females may still have reduced bone density.
Area of Science:
- Endocrinology
- Metabolic Disorders
- Bone Health
Background:
- Type I diabetes is a chronic metabolic disorder affecting various bodily functions.
- Bone health is a recognized concern in individuals with diabetes mellitus.
Purpose of the Study:
- To evaluate bone mineral content (BMC) in young patients with type I diabetes.
- To assess changes in BMC from disease onset and in long-term diabetic patients.
Main Methods:
- Bone mineral content (BMC) was measured using single photon absorptiometry.
- A prospective study followed 48 patients from diabetes onset for three years.
- A cross-sectional study evaluated 66 long-term diabetic patients.
Main Results:
- At disease onset, only two patients had low BMC.
- After three years, no males had low BMC, but 6.6% of females did.
- The cross-sectional study revealed reduced BMC in 12% of long-term diabetics.
- No correlation was found between bone deficit and diabetes duration or HbA1 levels.
Conclusions:
- Bone mineral content in young patients with type I diabetes shows a tendency to normalize over time, particularly in males.
- A small percentage of young females with type I diabetes may experience persistent low bone mineral content.
- Diabetes duration and glycemic control (HbA1) did not appear to be directly related to bone mass in this cohort.