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Updated: May 17, 2026

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury

Published on: January 20, 2023

Anesthesia awareness-induced posttraumatic stress disorder.

Kathleen M Prendergast¹, Mary Cullen-Drill

¹College of Nursing, Rutgers-The State University of New Jersey, Newark, NJ 07006, USA. kmprendergast@comcast.net

Journal of Psychosocial Nursing and Mental Health Services

|October 17, 2012

Summary

This summary is machine-generated.

Anesthesia awareness can lead to posttraumatic stress disorder (PTSD). This case study shows a 10-year PTSD treatment using psychotherapy, education, medication, and group therapy, highlighting the need for more research.

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Last Updated: May 17, 2026

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury

Published on: January 20, 2023

Area of Science:

Anesthesiology
Psychiatry
Trauma Studies

Background:

Anesthesia awareness, though documented, rarely has associated posttraumatic stress disorder (PTSD) research.
Limited information exists on effective treatments for PTSD specifically induced by anesthesia awareness.

Observation:

This article details a 10-year case of anesthesia awareness-induced PTSD in a female patient.
The patient experienced persistent PTSD symptoms following an anesthesia awareness event.

Findings:

A multimodal treatment approach was employed, including supportive psychotherapy, psychoeducation, psychopharmacology, and group therapy.
The patient demonstrated a positive response to the integrated treatment strategy.

Implications:

This case suggests that a combination of therapies can be effective for anesthesia awareness-induced PTSD.
Further research is crucial to establish optimal and evidence-based treatment protocols for this specific patient population.