Related Experiment Video
Updated: May 17, 2026

Assessment of Pulmonary Capillary Blood Volume, Membrane Diffusing Capacity, and Intrapulmonary Arteriovenous Anastomoses During Exercise
Published on: February 20, 2017
The evolution of exercise capacity and its limiting factors in cystic fibrosis
Athari Almajed1, Larry C Lands
1Division of Pediatric Respiratory Medicine, Department of Pdiatrics, Montreal Children's Hospital-McGill University Health Centre, 2300 Tupper Street, Room D380, Montreal, Québec, Canada, H3H 1P3.
Abstract:
The ability to perform exercise is an important determinant of both longevity and quality of life for patients with Cystic Fibrosis. There are a variety of physical and behavioural factors that contribute to exercise limitation. These, such as lung function or habitual physical activity, change over time. However, these factors can also be modified by treatments and interventions. This review discusses the various factors that contribute to exercise limitation in Cystic Fibrosis, and how these change with age.
More Related Videos
08:00Generation of Human Nasal Epithelial Cell Spheroids for Individualized Cystic Fibrosis Transmembrane Conductance Regulator Study
Published on: April 11, 2018
07:26Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
Published on: October 17, 2018
Related Concept Videos
Cystic Fibrosis: Pathogenesis
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation, but...
Cystic Fibrosis: Management
Sinus disease and chronic sinusitis...
Lung Capacity
Exercise and Muscle Performance
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Respiratory Capacities
One key metric is the Inspiratory Capacity (IC), which represents the maximum amount of air that can be inhaled with full effort. IC is calculated by summing the tidal volume and inspiratory reserve volume, typically ranging from 2.4 to 3.6 liters.
The Functional Residual Capacity (FRC) represents the air in the...
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation