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Related Concept Videos

Bacterial Signaling01:30

Bacterial Signaling

Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...
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Yeast Signaling

Yeasts are single-celled organisms, but unlike bacteria, they are eukaryotes (cells with a nucleus). Cell signaling in yeast is similar to signaling in other eukaryotic cells. A ligand, such as a protein or a small molecule released from a yeast cell, attaches to a receptor on the cell surface. The binding stimulates second-messenger kinases to activate or inactivate transcription factors that further regulate gene expression. Many of the yeast intracellular signaling cascades have similar...
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What is Cell Signaling?02:03

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Endocrine Signaling01:45

Endocrine Signaling

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Intracellular Signaling Cascades01:24

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Transient Transduction of the Strobilated Forms of Echinococcus granulosus
13:25

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Published on: September 16, 2022

[The signaling systems in Echinococcus multilocularis].

Xing-Wei Ni1, Hong-Bin Yan, Zhong-Zi Lou

  • 1State Key Laboratory of Veterinary Etiological Biology/Key Laboratory of Veterinary Parasitology of Gansu Province/Key Laboratory of Zoonoses of Agriculture Ministry/Lanzhou Veterinary Research Institute, CAAS, Lanzhou 730046, China.

Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi = Chinese Journal of Parasitology & Parasitic Diseases
|October 18, 2012
PubMed
Summary
This summary is machine-generated.

Parasitic infections like Echinococcus multilocularis hijack host cell signaling pathways for growth. Targeting these pathways with drugs could control alveolar echinococcosis.

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Area of Science:

  • Cell biology
  • Parasitology
  • Immunology

Context:

  • Echinococcus multilocularis infection triggers host and parasite cells to secrete cytokines, including insulin.
  • These cytokines act as signaling molecules, binding to cell receptors.
  • This process facilitates parasite growth and proliferation within the host.

Purpose:

  • To investigate the role of cellular signaling pathways in Echinococcus multilocularis infection.
  • To identify potential therapeutic targets for controlling alveolar echinococcosis.

Summary:

  • Cellular signaling pathways mediate responses to external stimuli, influencing cell proliferation, differentiation, and apoptosis.
  • During Echinococcus multilocularis infection, cytokines like insulin are secreted, activating signaling pathways.
  • This activation promotes parasite survival and multiplication within the host organism.

Impact:

  • Understanding these signaling mechanisms is crucial for developing novel treatment strategies.
  • Identifying drugs that block critical signaling pathways could lead to effective control of alveolar echinococcosis.
  • This research contributes to the fields of parasitic disease control and drug discovery.