Related Experiment Video
Updated: May 17, 2026
10:25
Isolation of Intact Mitochondria from Skeletal Muscle by Differential Centrifugation for High-resolution Respirometry Measurements
Published on: March 8, 2017
[Magnesium level in human organism during 105-day isolation].
Aviakosmicheskaia I Ekologicheskaia Meditsina = Aerospace and Environmental Medicine
|October 19, 2012
Summary
This study monitored magnesium levels during a 105-day isolation experiment. Ionized magnesium in serum and urine decreased, indicating stress and potential kidney function changes.
Area of Science:
- Biomedical science
- Human physiology
- Space medicine
Context:
- Investigating physiological responses to prolonged isolation and confinement.
- Simulating conditions relevant to long-duration space missions (Mars-105 experiment).
Purpose:
- To assess changes in total and ionized magnesium levels in serum and urine during isolation.
- To evaluate magnesium levels in hair as a biomarker.
- To determine if magnesium levels correlate with stress resistivity.
Summary:
- Magnesium levels in blood serum and daily urine were measured before and during a 105-day isolation experiment.
- Atomic emission spectrometry with inductively coupled argon plasma was used for analysis.
- A significant reduction in serum magnesium, primarily the ionized fraction, was observed within the first 30 days.
Impact:
- Identified a decrease in ionized magnesium during isolation, suggesting a physiological stress response.
- Highlighted the role of kidney function in magnesium regulation.
- Proposed ionized magnesium levels as potential indicators of stress resilience.
