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Insight in schizophrenia: associations with empathy
G H M Pijnenborg1, J M Spikman, B F Jeronimus
1Department of Psychotic Disorders, GGZ-Drenthe, Dennenweg 9, 9404 LA Assen, The Netherlands. g.h.m.pijnenborg@rug.nl
Impaired insight in schizophrenia is common. This study found that affective empathy and affective Theory of Mind (ToM) are key factors associated with better insight in schizophrenia patients.
Area of Science:
- Neuroscience
- Psychiatry
- Social Cognition
Background:
- Impaired insight is prevalent in schizophrenia (50-80%), linked to poorer outcomes.
- Empathy comprises affective (shared emotions) and cognitive (Theory of Mind/ToM) components.
- While ToM's link to insight is known, affective empathy's role in schizophrenia insight remains unexplored.
Purpose of the Study:
- To investigate the relationship between affective empathy, cognitive ToM, and affective ToM with insight in schizophrenia.
- To determine if affective empathy is more strongly associated with insight than ToM components.
Main Methods:
- Forty-six schizophrenia patients and 53 healthy controls were assessed.
- A comprehensive test battery included social cognition (affective empathy, ToM, emotion perception), memory, executive function, and intelligence.
- Insight was measured using the PANSS G12 item.
Main Results:
- Affective empathy demonstrated the strongest unique contribution to insight.
- Affective Theory of Mind (ToM) showed the second-strongest unique contribution.
- Together, affective empathy and affective ToM explained 45% of the variance in insight; other factors were not significant predictors.
Conclusions:
- Both affective empathy and affective ToM are significantly associated with insight in schizophrenia.
- Enhanced ability to empathize affectively and cognitively may improve insight in individuals with schizophrenia.
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