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Published on: April 23, 2019
Mapping the spread of methamphetamine abuse in California from 1995 to 2008
Paul J Gruenewald1, William R Ponicki, Lillian G Remer
1Prevention Research Center, Pacific Institute for Research and Evaluation, Berkeley, CA 94704, USA. paul@prev.org
Objectives:
From 1983 to 2008, the incidence of methamphetamine abuse and dependence (MA) presenting at hospitals in California increased 13-fold. We assessed whether this growth could be characterized as a drug epidemic.
Methods:
We geocoded MA discharges to residential zip codes from 1995 through 2008. We related discharges to population and environmental characteristics using Bayesian Poisson conditional autoregressive models, correcting for small area effects and spatial misalignment and enabling an assessment of contagion between areas.
Results:
MA incidence increased exponentially in 3 phases interrupted by implementation of laws limiting access to methamphetamine precursors. MA growth from 1999 through 2008 was 17% per year. MA was greatest in areas with larger White or Hispanic low-income populations, small household sizes, and good connections to highway systems. Spatial misalignment was a source of bias in estimated effects. Spatial autocorrelation was substantial, accounting for approximately 80% of error variance in the model.
Conclusions:
From 1995 through 2008, MA exhibited signs of growth and spatial spread characteristic of drug epidemics, spreading most rapidly through low-income White and Hispanic populations living outside dense urban areas.
Insights
Methamphetamine abuse and dependence (MA) in California grew exponentially, exhibiting characteristics of a drug epidemic. This epidemic spread rapidly, particularly among low-income White and Hispanic populations outside urban centers.
Area of Science:
- Epidemiology
- Public Health
- Substance Abuse Research
Background:
- Methamphetamine abuse and dependence (MA) incidence in California hospitals surged 13-fold between 1983 and 2008.
- The rapid increase prompted an investigation into whether this trend represented a drug epidemic.
Purpose of the Study:
- To assess if the escalating incidence of methamphetamine abuse and dependence (MA) in California aligns with the characteristics of a drug epidemic.
- To identify demographic and environmental factors associated with the spatial spread of MA.
Main Methods:
- Geocoding of MA hospital discharges to residential zip codes from 1995-2008.
- Utilizing Bayesian Poisson conditional autoregressive models to analyze relationships between MA incidence, population, and environmental factors.
- Accounting for small area effects, spatial misalignment, and assessing contagion between geographic areas.
Main Results:
- MA incidence demonstrated exponential growth in three distinct phases, interspersed with legislative interventions targeting precursor access.
- Annual MA growth averaged 17% from 1999 to 2008.
- Higher MA rates were observed in areas with significant low-income White and Hispanic populations, smaller households, and robust highway connectivity. Spatial autocorrelation explained approximately 80% of the model's error variance.
Conclusions:
- From 1995 to 2008, methamphetamine abuse and dependence (MA) in California displayed epidemic-like growth and spatial diffusion patterns.
- The epidemic spread most rapidly through low-income White and Hispanic communities situated in non-urbanized regions.
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