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Updated: May 17, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

Cardiac resynchronization therapy for patients with congenital heart disease: technical challenges

Meera Manchanda1, Christopher J McLeod, Ammar Killu

  • 1Division of Cardiovascular Diseases, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing
|October 20, 2012
PubMed

Insights

Cardiac resynchronization therapy (CRT) offers hope for heart failure (HF) patients. This review explores CRT

Area of Science:

  • Cardiology
  • Adult Congenital Heart Disease

Background:

  • Adult congenital heart disease (CHD) survival is increasing.
  • These patients may develop heart failure (HF) and ventricular dysfunction.
  • Cardiac resynchronization therapy (CRT) is an option for HF management.

Purpose of the Study:

  • To review unique features of CRT in adult CHD patients.
  • To examine current data on CRT utilization in this population.
  • To discuss limitations and technical considerations for CRT in CHD.

Main Methods:

  • Literature review of existing data on CRT in adult CHD.
  • Analysis of utilization, benefits, and data availability.
  • Review of coronary sinus anatomy and LV lead placement in CHD.

Main Results:

  • Limited data exists on CRT utilization and benefits in adult CHD.
  • Specific anatomical challenges exist for LV lead placement.
  • Further research is needed to optimize CRT in this population.

Conclusions:

  • CRT may benefit select adult CHD patients with HF.
  • Careful patient selection and technical considerations are crucial.
  • More research is required to establish optimal CRT strategies for CHD.

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