Catheter-Based Radiofrequency Ablation for Subaortic Membrane
James F Howick V1, Lara Dando1, Jeanwoo Yoo1
1Department of Cardiovascular Medicine, Mayo Clinic, Jacksonville, Florida, USA.
Background:
Patients with symptomatic subaortic membrane obstruction require open surgical intervention, and often an extensive Konno procedure is required. Catheter-based intervention has not been utilized in this therapeutic context.
First-In-Human/Early Reports Summary:
A 53-year-old man with recurrent symptomatic subaortic membrane following prior surgical resection underwent catheter-based radiofrequency (RF) ablation resulting in sustained left ventricular outflow tract gradient reduction and improved symptoms.
Discussion:
This case demonstrates the safety, feasibility, and short-term efficacy of RF ablation in managing fixed left ventricular outflow tract obstruction from recurrent subaortic membrane.
Novelty:
Catheter-based approaches have not been previously utilized to address subaortic membrane obstruction.
Take-Home Message:
Transcatheter RF ablation may offer a safe, minimally invasive option for select patients with recurrent subaortic membrane obstruction.


