Related Experiment Video
Updated: May 17, 2026
Method of Studying Palatal Fusion using Static Organ Culture
Published on: September 19, 2015
A descriptive epidemiologic study of cleft lip and palate in Spain
Rosa-María Yáñez-Vico1, Alejandro Iglesias-Linares, Ignacio Gómez-Mendo
1School of Dentistry, University of Seville, Seville, Spain. rosayanezvico@gmail.com
Objective:
The purpose of this study was to investigate the distribution of different cleft patterns by sex, side of the cleft, and family history of clefts in a referral hospital in the south of Spain.
Study Design:
One hundred twenty-three consecutive cleft lip subjects, with or without palates, attending the Stomatology Unit in the Virgen del Rocío University Hospital and in the Virgen Macarena University Hospital from October 2009 to May 2010 were studied.
Results:
The unilateral complete cleft lip and palate (54.4%) was most frequently found, followed by the bilateral complete cleft lip and palate (16.3%). Male patients (60.97%) and the left side (41.46%) were the most affected. A positive family history was observed in 21.94% of subjects.
Conclusions:
The most frequent profile in the affected population was male with left unilateral complete cleft lip and palate. The high incidence of family history of cleft on the father's side prompts us to recommend further genetic research in this area.
