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Updated: May 17, 2026

The ITS2 Database
Published on: March 12, 2012
Highlights from the International Transporter Consortium second workshop
M J Zamek-Gliszczynski1, K A Hoffmaster, D J Tweedie
1Drug Disposition, Lilly Research Laboratories, Indianapolis, Indiana, USA. m_zamek-gliszczynski@lilly.com
Abstract:
The Second International Transporter Consortium (ITC) Workshop was held with the purpose of expanding on previous white-paper recommendations, discussing recent regulatory draft guidance documents on transporter-drug interactions, and highlighting transporter-related challenges in drug development. Specific goals were to discuss additional clinically relevant transporters (MATEs, MRP2, BSEP) and best-practice methodologies and to re-evaluate ITC decision trees based on actual case studies. The outcome of the workshop will be a series of white papers targeted for publication in 2013.
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