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Published on: October 6, 2023
Acylcarnitine profile in thyroid disease
Sophia Wong1, Fady Hannah-Shmouni, Graham Sinclair
1Division of Medical Biochemistry, Department of Pathology and Laboratory Medicine, St. Paul's Hospital, Vancouver, Canada. Wong.Sophia@gmail.com
Objectives:
To examine acylcarnitine profiles in individuals with hypo- or hyperthyroidism, and determine whether any atypical acylcarnitine species identified would normalize with correction of thyroid status.
Design And Methods:
Serum acylcarnitine levels were measured in hypo- and hyperthyroid subjects before and after treatment with thyroxine or thionamide therapy respectively.
Results:
No discernible differences were observed in the serum acylcarnitine profiles between hypo-, hyper- and euthyroid states.
Conclusions:
Acylcarnitine profiles are relatively unremarkable in thyroid disease.
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