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Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing

Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing

Published on: October 10, 2025

[Lung cancer, a worrying epidemiological evolution].

Catherine Daniel¹

¹Institut Curie, Paris. catherine.daniel@curie.net

Revue De L'Infirmiere

|October 25, 2012

Summary

This summary is machine-generated.

Most lung cancers are diagnosed late due to the lack of screening tests, negatively impacting patient prognosis. The rising incidence, particularly among women, presents a significant public health concern for lung cancer epidemiology.

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Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

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Published on: September 20, 2016

Area of Science:

Oncology
Epidemiology
Public Health

Context:

Lung cancer diagnosis often occurs at advanced stages (locally advanced or metastatic) due to the absence of effective screening methods.
Late-stage diagnosis significantly worsens patient prognosis and survival rates.
There is a concerning epidemiological trend showing an increasing incidence of lung cancer, especially in women.

Purpose:

To highlight the diagnostic challenges in lung cancer.
To underscore the negative prognostic implications of late-stage diagnosis.
To draw attention to the escalating lung cancer rates among women.

Summary:

The lack of a screening test leads to delayed diagnosis of lung cancer, typically at locally advanced or metastatic stages.
This delay adversely affects patient outcomes and survival.
The increasing prevalence of lung cancer, particularly in the female population, is a critical public health issue.

Impact:

Emphasizes the urgent need for developing effective lung cancer screening strategies.
Underscores the importance of early detection for improving lung cancer patient outcomes.
Calls for targeted public health interventions to address the rising lung cancer burden in women.