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Updated: May 17, 2026

Operating Transverse Aortic Constriction with Absorbable Suture to Obtain Transient Myocardial Hypertrophy
Published on: September 9, 2020
Extended myectomy for hypertrophic obstructive cardiomyopathy.
Changqing Gao1, Chonglei Ren, Cangsong Xiao
1Department of Cardiovascular Surgery, General Hospital of PLA, Institute of Cardiac Surgery of PLA, Beijing, China. gaochq301@yahoo.com
Extended ventricular septal myectomy effectively treats hypertrophic obstructive cardiomyopathy (HOCM) by significantly reducing left ventricular outflow tract obstruction and improving patient symptoms. Thorough septal excision is key to successful surgical outcomes.
Area of Science:
- Cardiology
- Cardiac Surgery
- Medical Devices
Background:
- Hypertrophic obstructive cardiomyopathy (HOCM) is characterized by left ventricular hypertrophy and outflow tract obstruction.
- Systolic anterior motion (SAM) of the mitral valve and mitral regurgitation are common complications in HOCM patients.
Purpose of the Study:
- To summarize the surgical experience with extended ventricular septal myectomy in patients diagnosed with HOCM.
- To evaluate the efficacy and safety of this surgical approach for HOCM treatment.
Main Methods:
- Thirty-eight HOCM patients underwent extended ventricular septal myectomy.
- Preoperative and postoperative echocardiography (transesophageal and transthoracic) assessed systolic gradients and septal thickness.
- Intraoperative and follow-up assessments evaluated surgical outcomes, including SAM and mitral regurgitation.
Main Results:
- Extended ventricular septal myectomy significantly reduced mean systolic gradients from 94.8 mm Hg to 13.6 mm Hg (P=.0000).
- Ventricular septal thickness decreased from 28.3 mm to 11.8 mm (P=.0000), with significant reduction or elimination of SAM and mitral regurgitation.
- All patients experienced symptom resolution or improvement, with abolished syncope and reduced dyspnea.
Conclusions:
- Extended ventricular septal myectomy is a highly effective treatment for HOCM.
- Achieving adequate surgical exposure and performing thorough excision of the hypertrophic septum are critical for successful outcomes.
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