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Updated: May 17, 2026

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Published on: October 28, 2021

Primary intravascular synovial sarcoma: case report.

Osman Nuri Tuncer¹, Ozan Erbasan, Ilhan Golbasi

¹Department of Cardiovascular Surgery, Faculty of Medicine, Akdeniz University, Antalya, Turkey. dr_ osmantuncer@hotmail.com

The Heart Surgery Forum

|October 25, 2012

Summary

This summary is machine-generated.

This study reports an extremely rare case of intravascular synovial sarcoma (IVSS) in a 16-year-old boy. The successful surgical excision of the IVSS in the superior vena cava highlights a rare but treatable soft-tissue sarcoma presentation.

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Last Updated: May 17, 2026

Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models

Intratibial Osteosarcoma Cell Injection to Generate Orthotopic Osteosarcoma and Lung Metastasis Mouse Models

Published on: October 28, 2021

Area of Science:

Oncology
Pathology
Genetics

Background:

Synovial sarcoma (SS) is a soft-tissue sarcoma characterized by the specific t(X;18)(p11;q11) chromosomal translocation.
While SS commonly occurs near joints, intravascular synovial sarcoma (IVSS) is exceptionally rare, with limited documented cases.

Observation:

A 16-year-old male presented with a large mass in the right atrium, extending from the superior vena cava (SVC) to the tricuspid valve.
Diagnostic imaging revealed a significant pericardial effusion and a mass measuring 4.8 × 4.6 cm within the heart.
Surgical exploration identified an 8 to 12 cm tumor attached to the SVC via a narrow pedicle.

Findings:

Surgical excision of the IVSS via a transatrial approach was successfully performed.
Postoperative recovery was uneventful.
Fluorescence in situ hybridization confirmed the presence of the SS-specific translocation in the excised tumor.

Implications:

This case expands the known clinical spectrum of synovial sarcoma, particularly its rare intravascular presentation.
Highlights the importance of considering rare diagnoses in complex cases, even with atypical locations.
Demonstrates the feasibility of surgical management for IVSS originating in major vessels like the SVC.