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Thrombocytopenia in the setting of hemodialysis using biocompatible membranes

Kathryn B Muir1, Clifford D Packer

  • 1School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.

Case Reports in Medicine
|October 25, 2012
PubMed

Thrombocytopenia is a known potential side effect of hemodialysis, however, it is rarely seen in patients who undergo hemodialysis using biocompatible membranes. This case demonstrates hemodialysis-associated thrombocytopenia with use of biocompatible dialysis membranes that expose blood directly to polysulfone. The thrombocytopenia resolved in this patient when the dialysis membrane was changed to a biocompatible model with a polyethylene glycol barrier layer preventing direct interaction between patient blood and polysulfone. The calculated Naranjo ADR score of 9 indicates a highly probable adverse reaction.

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